• Title of article

    Synthesis of (4R*,5S*)-5-acetylamino-4-diethylcarbamoyl-5,6-dihydro-4H-pyran-2-carboxylic acid and its inhibitory action against influenza virus sialidases

  • Author/Authors

    Kerrigan، نويسنده , , Sean A and Pritchard، نويسنده , , Robin A. J. Smith، نويسنده , , Paul W and Stoodley، نويسنده , , Richard J، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    8889
  • To page
    8892
  • Abstract
    (4R*,5S*)-5-Acetylamino-4-diethylcarbamoyl-5,6-dihydro-4H-pyran-2-carboxylic acid has been synthesised from methyl (E)-4-diethylcarbamoyl-2-oxobut-3-enoate and 2-nitroethanol; the acid is a moderately active inhibitor of influenza A sialidase.
  • Keywords
    Pyrans , antivirals , Cyclisation , enones , Michael reactions , Nitro compounds
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1648667

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1648667