Title of article :
Polymer-assisted solution-phase parallel synthesis of dipeptide p-nitroanilides and dipeptide diphenyl phosphonates
Author/Authors :
Kristel Senten، نويسنده , , Kristel and Van der Veken، نويسنده , , Pieter and Bal، نويسنده , , Gunther and Haemers، نويسنده , , Achiel and Augustyns، نويسنده , , Koen، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
This letter describes the parallel synthesis of dipeptide p-nitroanilides (1) and dipeptide diphenyl phosphonates (2), compounds that can be used as substrates and irreversible inhibitors for the rapid profiling of dipeptidyl peptidases. A polymer-assisted solution-phase synthesis was used for a rapid and clean coupling between easily available building blocks.
Keywords :
dipeptide p-nitroanilides , amide coupling , dipeptide diphenyl phosphonates , polymer-assisted solution-phase synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
