Application of the double intramolecular hetero-Michael addition (DIHMA) approach in spiroketal synthesis: total synthesis of (±)-(4S*,6S*)-4-hydroxy-1,7-dioxaspiro[5.5]undecane, a Dacus oleae olive fly pheromone

Application of a novel double intramolecular hetero-Michael addition (DIHMA) strategy to spiroketal synthesis was illustrated by a concise synthesis of (±)-(4S*,6S*)-4-hydroxy-1,7-dioxaspiro[5.5]undecane, a Dacus oleae olive fly pheromone.