Title of article
Microwave-assisted synthesis of 2-aminoquinolines
Author/Authors
Wilson، نويسنده , , Noel S and Sarko، نويسنده , , Christopher R and Roth، نويسنده , , Gregory P، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
581
To page
583
Abstract
An improved method for the synthesis of 2-aminoquinolines utilizing microwave-assisted synthesis is described. The process involves rapid microwave irradiation of secondary amines and aldehydes to form enamines followed by the addition of 2-azidobenzophenones with subsequent irradiation to produce the 2-aminoquinoline derivatives. Purification of the products is accomplished in a streamlined manner using solid-phase extraction techniques to produce the desired products in high yields and purity.
Keywords
2-aminoquinolines , Microwave-assisted synthesis , Combinatorial chemistry
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1649388
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