Author/Authors :
Routier، نويسنده , , Sylvain and Saugé، نويسنده , , Laurence and Ayerbe، نويسنده , , Nathalie and Coudert، نويسنده , , Gérard and Mérour، نويسنده , , Jean-Yves، نويسنده ,
Abstract :
A new mild method to remove N-tert-butyloxycarbonyl groups using TBAF in refluxing THF is reported. In all cases, the corresponding N-free products are obtained in good yields. The reactions are selective for acid- and base-sensitive groups, such as tert-butyl and alkyl esters, aldehydes.
