Chemical synthesis of an oligodeoxythymidylate containing boranephosphate and phosphate linkages
Author/Authors :
Brummel، نويسنده , , Heather A. and Caruthers، نويسنده , , Marvin H.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
3
From page :
749
To page :
751
Abstract :
Oligodeoxythymidylate 14mers containing combinations of boranephosphate and phosphate linkages have been synthesized. These compounds show improved binding affinity and RNase H activation over fully modified boranephosphate DNA.
