Title of article
An efficient method for the preparation of antitumoral α-keto-imines benzyldihydroisoquinolines by selective benzylic oxidation with C/Pd in acetonitrile
Author/Authors
Andreu ، نويسنده , , Inmaculada and Cabedo، نويسنده , , Nuria and Atassi، نويسنده , , Ghanem and Pierre، نويسنده , , Alain and Caignard، نويسنده , , Daniel H and Renard، نويسنده , , Pierre and Cortes، نويسنده , , Diego and Bermejo، نويسنده , , Almudena، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
757
To page
759
Abstract
A series of potent antitumor α-keto-imine BDHIQ derivatives were synthesized and assayed in vitro against L1210 leukemia cell line. A new and easy method for the direct formation of α-keto-imine from imine BDHIQʹs was performed with 10% C/Pd in acetonitrile.
Keywords
benzyldihydroisoquinolines , ?-keto-imines , C/Pd , Acetonitrile , Selective oxidation , Antitumoral
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1649534
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