Title of article :
Intramolecular TiCl4-mediated cyclization reaction of β-hydroxy alkynyl acetals
Author/Authors :
Kim، نويسنده , , Yong-Hyun and Lee، نويسنده , , Kee-Young and Oh، نويسنده , , Chang-Young and Yang، نويسنده , , Jae-Gwon and Ham، نويسنده , , Won-Hun Ham، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Intramolecular TiCl4-mediated cyclization reaction of 1,1-dimethoxy-3-hydroxy-hex-5-yne derivatives produced anti-1-hydroxy-3-methoxy-cyclohex-5-ene derivatives with high diastereoselectivity via antiperiplanar manner on pseudo six-membered chair like conformation (transition state A).
Keywords :
3-diaxial alcohol , ?-hydroxy alkynyl acetal , stereocontrol , Intramolecular cyclization , 1 , Lewis acid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
