Author/Authors :
Wang، نويسنده , , De-Xin and Liang، نويسنده , , Ming-Tao and Tian، نويسنده , , Gui-Jie and Lin، نويسنده , , Hao and Liu، نويسنده , , Hong-Qiang، نويسنده ,
Abstract :
Eighteen diketopiperazines (DKPs) were synthesized in good yields by a solid-phase protocol. This synthesis reveals that the OPac linker between the peptidyl and resin support is favorable to DKP-ring formation and offers a facile and effective way to prepare diverse DKP libraries for combinatorial chemistry.