Author/Authors :
Ryu، نويسنده , , Ilhyong and Ikebe، نويسنده , , Masanobu and Sonoda، نويسنده , , Noboru and Yamato، نويسنده , , Shin-ya and Yamamura، نويسنده , , Go-hei and Komatsu، نويسنده , , Mitsuo، نويسنده ,
Abstract :
The cross-coupling reaction of dianion cuprates, generated from ketone α,β-dianions and copper salts, with acid chlorides, was studied. The reaction gave good to moderate yields of unsymmetrical 1,4-diketones. The consecutive treatment of a dianion cuprate with cyclohexanecarbonyl chloride and methyl iodide or two different acid chlorides gave 2-methyl-substituted 1,4-diketone or triketone, respectively.
