Title of article :
High pressure activation in the asymmetric Michael addition of chiral imines to alkyl and aryl crotonates
Author/Authors :
Camara، نويسنده , , Cheikhou and Joseph، نويسنده , , Delphine and Dumas، نويسنده , , Françoise and dʹAngelo، نويسنده , , Jean and Chiaroni، نويسنده , , Angèle، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
High pressure-mediated Michael addition of chiral imines derived from 2-methylcyclopentanone, 2-methylcyclohexanone and optically active 1-phenylethylamine, to methyl and phenyl crotonates was investigated. The corresponding adducts were obtained in fair yields and with a high degree of regio-, diastereo- and enantioselectivity.
Keywords :
diastereoselection , Enantioselection , imines , Pressure , reactions under , Michael reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
