• Title of article

    A convenient procedure for the preparation of α-aminoallenes using a three-component reaction of aldehyde, carbamate and propargylsilane

  • Author/Authors

    Billet، نويسنده , , Manuella and Schoenfelder، نويسنده , , Angèle and Klotz، نويسنده , , Philippe and Mann، نويسنده , , André، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    1453
  • To page
    1456
  • Abstract
    A three-component reaction is described using an aldehyde, a carbamate and trimethylpropargylsilane in the presence of a Lewis acid for the production in moderate to good yield of α-allenyl amines. The reaction is applicable to aromatic or aliphatic aldehydes. The obtained α-aminoallenes are transformed into Δ3-pyrrolidines or amino acids by using the reactivity of the cumulene function.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1650061