Author/Authors :
Billet، نويسنده , , Manuella and Schoenfelder، نويسنده , , Angèle and Klotz، نويسنده , , Philippe and Mann، نويسنده , , André، نويسنده ,
Abstract :
A three-component reaction is described using an aldehyde, a carbamate and trimethylpropargylsilane in the presence of a Lewis acid for the production in moderate to good yield of α-allenyl amines. The reaction is applicable to aromatic or aliphatic aldehydes. The obtained α-aminoallenes are transformed into Δ3-pyrrolidines or amino acids by using the reactivity of the cumulene function.
