Title of article
Liquid-phase combinatorial reaction monitoring by conventional 1H NMR spectroscopy
Author/Authors
Shey، نويسنده , , Jing-Ying and Sun، نويسنده , , Chung-Ming، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
1725
To page
1729
Abstract
The application of 1H NMR spectroscopy for complete analysis of soluble polymer-supported reactions is described. This conventional analytical technique enables us to determine the extent of liquid-phase reactions without cleavage of the soluble matrix. The polymer matrix permitted us to obtain 1H NMR spectra with a resolution comparable with that of spectra of the molecule in solution.
Keywords
Combinatorial chemistry , Liquid-phase synthesis , Substitution , NMR , cleavage
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650277
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