Title of article
Synthesis of new chiral imidazolidine disulfides derived from l-cystine and their application in the enantioselective addition of diethylzinc to aldehydes
Author/Authors
Braga، نويسنده , , Antonio J. Moreno-Vargas، نويسنده , , Fabr??cio and Silveira، نويسنده , , Claudio C and de Andrade، نويسنده , , Leandro H، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
2335
To page
2337
Abstract
Several chiral imidazolidine disulfides 4a–d derived from l-cystine have been synthesized. These ligands have been applied as chiral catalysts in the asymmetric addition of diethylzinc to aldehydes. The best results were obtained by employing 5 mol% of imidazolidine disulfide 4a, and chiral secondary alcohols were obtained in up to 91% e.e.
Keywords
Chiral ligands , enantioselective addition , disulfides , l-cystine , Imidazolidine
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650715
Link To Document