Title of article :
Synthesis and applications of propargyl pentafluorophenyl carbonate for peptide synthesis
Author/Authors :
Bhat، نويسنده , , Ramakrishna G and Kérourédan، نويسنده , , Erwan and Porhiel، نويسنده , , Emmanuel and Chandrasekaran، نويسنده , , Srinivasan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Propargyl pentafluorophenyl carbonate was synthesised in quantitative yield by the reaction of propargyl chloroformate and pentafluorophenol. All the N-propargyloxycarbonyl (N-Poc) amino acids were obtained in good yield. The use of Poc-OPfp in peptide synthesis has been explored.
Keywords :
protecting groups , propargyl pentafluorophenyl carbonate , tetrathiomolybdate , amino acids , peptide synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
