Title of article
Development of 5-(aminomethyl)pyrrole-2-carboxylic acid as a constrained surrogate of Gly-ΔAla and its application in peptidomimetic studies
Author/Authors
Chakraborty، نويسنده , , Tushar K and Krishna Mohan، نويسنده , , B and Kiran Kumar، نويسنده , , S and Kunwar، نويسنده , , Ajit C، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
2589
To page
2592
Abstract
A new peptidomimetic scaffold based on 5-(aminomethyl)pyrrole-2-carboxylic acid (1) is developed for the first time and used as a conformationally constrained surrogate of the Gly-ΔAla dipeptide isostere (2) to prepare peptides 3 and 4.
Keywords
Dehydro amino acids , peptide mimetics , Hydrogen bonding , Conformation , NMR
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650890
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