Title of article
Practical synthesis of chiral ligands for catalytic enantioselective cyanosilylation of ketones
Author/Authors
Masumoto، نويسنده , , Shuji and Yabu، نويسنده , , Kazuo and Kanai، نويسنده , , Motomu and Shibasaki، نويسنده , , Masakatsu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
2919
To page
2922
Abstract
A practical and more environmentally benign synthetic route of chiral ligands that are useful for catalytic enantioselective cyanosilylation of ketones is described. A key step is the regioselective SN2 reaction to cyclic sulfate 12 with catechol derivatives. A range of chiral ligands containing electronically tuned catechols has become available by this new route.
Keywords
ketones , practical synthesis , ligand-tuning , chiral ligand , catalytic enantioselective reaction , Cyanosilylation , Cyclic sulfate
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651135
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