Title of article
Synthesis of new echinocandin derivatives via a diol-keto transposition
Author/Authors
Aszodi، نويسنده , , Jozsef and Fauveau، نويسنده , , Patrick and Melon-Manguer، نويسنده , , Dominique and Ehlers، نويسنده , , Eberhard and Schio، نويسنده , , Laurent، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
2953
To page
2956
Abstract
A new diol-carbonyl transposition reaction has been discovered in echinocandin type structures. An α-hydroxy hemiaminal moiety has been shown to undergo a pinacol-type rearrangement in the presence of trimethylsilyl iodide to afford ketone derivatives. Applied to deoxymulundocandin, this transposition led to a useful intermediate for further chemical modification.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651170
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