Author/Authors :
Qian، نويسنده , , Xuhong and Mao، نويسنده , , Ping and Yao، نويسنده , , Wei and Guo، نويسنده , , Xiangfeng، نويسنده ,
Abstract :
A novel hydroperoxide of benzothioxanthene dicarboximide B4 was synthesized through naphthyl radical-induced aromatic 1,5-hydrogen transfer in an unusual Pschorr cyclization and photooxygenation. It was evaluated as an excellent ‘time-resolved’ DNA photocleaver with long-wavelength absorption, which can photonick the duplex DNA at a micromolar concentration of 5 μM upon irradiation at 450 nm.
