• Title of article

    Efficient synthesis of quinazolinones as intermediates of CNS agents via inverse-electron demand Diels–Alder reaction

  • Author/Authors

    Bilbao، نويسنده , , Estibaliz R. and Alvarado، نويسنده , , Mario and Masaguer، نويسنده , , Christian F. and Raviٌa، نويسنده , , Enrique، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    3551
  • To page
    3554
  • Abstract
    Enaminones undergo inverse electron demand Diels–Alder reaction with 1,3,5-triazine, allowing access to functionalised quinazolinones as intermediates in the synthesis of CNS agents. This reaction is highly dependent of the solvent: 1,3,5-triazine undergoes single or double [4+2] cycloadditions with enaminones, and quinazolinones or acridinediones can be selectively obtained.
  • Keywords
    Diels–Alder reactions , Quinazolinones , triazines , Enamino ketones
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1651596