Title of article :
Enantioselective reduction of aryl ketones using LiBH4 and TarB-X: a chiral Lewis acid
Author/Authors :
Suri، نويسنده , , Jeff T and Vu، نويسنده , , Truong and Hernandez، نويسنده , , Arturo and Congdon، نويسنده , , Julie and Singaram، نويسنده , , Bakthan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
High enantioselectivities are obtained using a tartaric acid-derived boronate ester in combination with lithium borohydride for asymmetric reduction of aryl ketones. The chiral Lewis acid, TarB-X, is easily prepared in 1 h, and the resulting alcohols are obtained in enantiomeric excesses of 88–99%.
Keywords :
enantioselective , Tartaric acid , Boronic Acid , Reduction , chiral Lewis acid , asymmetric
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
