Preparation and conversion of chiral O-isopropylidene-protected 4-aminocyclohexenol to various key intermediates toward narcissus alkaloids

Enantiomerically pure 4-amino-5,6-O-isopropylidenedioxycyclohex-2-en-1-ol, conveniently prepared by the union of O-isopropylidenedioxycyclohexadiene with camphor-based chloronitroso ester, was employed in the synthesis of versatile key intermediates toward narcissus alkaloids.