Title of article
Microwave-assisted deuterium exchange reactions for the preparation of reactive intermediates
Author/Authors
Fodor-Csorba، نويسنده , , Katalin and Galli، نويسنده , , Giancarlo and Holly، نويسنده , , Sلndor and Gلcs-Baitz، نويسنده , , Eszter، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
3789
To page
3792
Abstract
Deuterium labelling of a number of ketones was achieved on a preparative scale by a microwave-assisted deuterium exchange reaction with D2O/CF3COOD. The reaction was rapid (<15 min) and highly isotope-efficient (ca. 100%), even though deuterium incorporation can be decreased during work-up (85–90%). No exchange reaction was observed for aryl protons of aromatic ketones.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651768
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