Title of article
Convenient synthesis of Cbz-protected β-amino ketones by a copper-catalysed conjugate addition reaction
Author/Authors
Wabnitz، نويسنده , , Tobias C and Spencer، نويسنده , , Jonathan B، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
3891
To page
3894
Abstract
A convenient synthesis of Cbz-protected β-amino ketones is reported. Benzyl carbamates and α,β-unsaturated ketones furnish the conjugate addition products in the presence of a Cu(II) catalyst under mild conditions. Other weakly basic nitrogen nucleophiles can also be used in this reaction.
Keywords
benzyl carbamate , conjugate addition , Copper , ?-amino ketones , nitrogen nucleophiles
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651839
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