Author/Authors :
He، نويسنده , , Jian and Zhong، نويسنده , , Wenwan and Tang، نويسنده , , Aijun and Yan، نويسنده , , Xiaomei and Lewis، نويسنده , , Cris and Majidi، نويسنده , , Vahid and Hang، نويسنده , , Wei، نويسنده ,
Abstract :
A system was proposed to remove the upper mass limitation of mass spectrometry. In present study, ultra large molecules were separated in the gas phase by mass analyzer after electrospray ionization. Instead of conventional detection with electron multiplier, a laser-induced-fluorescence detection scheme was applied. The instrument sensitivity is independent of molecular weight, but related to the spectroscopic properties of the fluorophores presented by the large biomolecules.
Keywords :
fluorescence detection , Ultra large molecules , mass spectrometry , Ion mobility spectrometry
