• Title of article

    Mesyl guaiacol: a versatile intermediate for the synthesis of 5-aminomethyl guaiacol and related compounds

  • Author/Authors

    Bensel، نويسنده , , Nicolas and Pevere، نويسنده , , Virginie and Desmurs، نويسنده , , Jean Roger and Wagner، نويسنده , , Alain and Mioskowski، نويسنده , , Charles، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    4281
  • To page
    4283
  • Abstract
    An original synthetic pathway for the preparation of 5-substituted guaiacol derivatives is described. This method relies on the deactivation of the phenol group by converting it into the corresponding mesyl ester. Amidomethylation reactions lead to regioselective CC bond formation at the 5-position of guaiacol. Thus, 5-aminomethyl-guaiacol was obtained in four steps and 75% overall yield.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1652119

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1652119