Title of article :
Allylsilane addition on C-13 of 11-methoxycarbonyl-17-acetyl-1,3,5(10),13(17)-gonatetraenes: a straightforward route to introduce an 18α-methyl group
Author/Authors :
Michellys، نويسنده , , Pierre-Yves and Maurin، نويسنده , , Philippe and Pellissier، نويسنده , , Hélène and Santelli، نويسنده , , Maurice، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
The conjugate addition of allylsilane (Sakurai reaction) to 11-methoxycarbonyl-17-acetyl-1,3,5(10),13(17)-gonatetraenes provided 13α-allyl steroids. Ozonolysis followed by a decarbonylation affords steroids exhibiting the 18α-methyl group. This new steroid is an estrone derivative.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
