Title of article :
Synthesis and conformation of a novel bridged nucleoside with S-type sugar puckering, trans-3′,4′-BNA monomer
Author/Authors :
Obika، نويسنده , , Satoshi and Sekiguchi، نويسنده , , Mitsuaki and Osaki، نويسنده , , Tomohisa and Shibata، نويسنده , , Nao and Masaki، نويسنده , , Miyuki and Hari، نويسنده , , Yoshiyuki and Imanishi، نويسنده , , Takeshi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
A novel bridged nucleoside bearing a 4,7-dioxabicyclo[4.3.0]nonane skeleton, trans-3′,4′-BNA monomer, was successfully synthesized. A 1H NMR experiment and an X-ray crystallographic analysis revealed that the sugar puckering of the 3′,4′-BNA monomer was restricted to an S-type (C3′-exo) conformation.
Keywords :
Conformation , nucleic acid analogues , X-ray crystal structures , nucleosides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
