Author/Authors :
Kawasaki، نويسنده , , Ikuo and Sakaguchi، نويسنده , , Norihiro and Fukushima، نويسنده , , Norie and Fujioka، نويسنده , , Naoko and Nikaido، نويسنده , , Fumi and Yamashita، نويسنده , , Masayuki and Ohta، نويسنده , , Shunsaku، نويسنده ,
Abstract :
Diels–Alder-type dimerization of various 5-ethenyl-2-phenylsulfanyl-1H-imidazoles provided a novel highly regio- and stereoselective route to the preparation of multifunctionalized 4,5,6,7-tetrahydrobenzimidazoles, the basic skeleton of ageliferin, a biologically active pyrrole–imidazole marine alkaloid. The reaction was applied to the synthesis of 12,12′-dimethylageliferin.
