Title of article
Conformational flexibility of inositol phosphates: influence of structural characteristics
Author/Authors
Volkmann، نويسنده , , Carla J. and Chateauneuf، نويسنده , , Ginger M. and Pradhan، نويسنده , , Jyotsna and Bauman، نويسنده , , Andrew T. and Brown، نويسنده , , Richard E. and Murthy، نويسنده , , Pushpalatha P.N. Murthy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
4853
To page
4856
Abstract
Dynamic NMR and molecular modeling techniques were employed to investigate the influence of structural characteristics on the ring inversion processes of inositol phosphates. The results indicate that inositol phosphates that contain the syn-1,3,5-triaxial trisphosphate arrangement show great proclivity to adopt the sterically hindered conformation. These results suggest that the ability to form chelation cages with counter-ions is a major factor in the ring inversion processes of inositol phosphates.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1652498
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