Title of article
An efficient solid-phase synthesis of 3-alkylamino-1,2,4-oxadiazoles
Author/Authors
Makara، نويسنده , , Gergely M and Schell، نويسنده , , Peter D. Hanson، نويسنده , , Kelley and Moccia، نويسنده , , Dennis، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
5043
To page
5045
Abstract
A solid-phase synthesis of substituted 3-alkylamino-1,2,4-oxadiazoles has been developed. The synthesis utilizes immobilized N-acyl-1H-benzotriazole-1-carboximidamides as key intermediates. Cyclization with hydroxylamine under mild conditions furnished the oxadiazole skeleton regioselectively in high yield and purity.
Keywords
Benzotriazole , solid-phase , Oxadiazole , combinatorial
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1652639
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