Title of article
Incorporation of three deuterium atoms excludes intermediacy of stilbenecarboxylic acid in stilbene synthase reaction
Author/Authors
Shibuya، نويسنده , , Masaaki and Nishioka، نويسنده , , Mizue and Sankawa، نويسنده , , Ushio and Ebizuka، نويسنده , , Yutaka، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
5071
To page
5074
Abstract
To investigate the mechanism of stilbene synthase (STS) reaction, the origin of the aromatic protons of resveratrol B-ring was examined using STS from Arachis hypogaea expressed in Escherichia coli and deuterated malonyl CoA. The presence of resveratrol labeled with three deuterium atoms was detected by GCMS analysis indicating decarboxylation earlier than aromatization, i.e. exclusion of intermediacy of stilbenecarboxylic acid in STS reaction.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1652663
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