• Title of article

    The first Bischler–Napieralski cyclization in a room temperature ionic liquid

  • Author/Authors

    Judeh، نويسنده , , Zaher M.A. and Ching، نويسنده , , Chi Bun and Bu، نويسنده , , Jie and McCluskey، نويسنده , , Adam، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    5089
  • To page
    5091
  • Abstract
    We have demonstrated the use of the room temperature ionic liquid, 1-butyl-3-methylimidazoliumhexafluorophosphate ([bmim]PF6), as an environmentally benign solvent for the preparation of isoquinoline derivatives through Bischler–Napieralski cyclization under mild conditions with excellent purity and yields. The role of HF as a catalyst in the reaction was also investigated.
  • Keywords
    Ionic liquids , Bischler–Napieralski cyclization , Isoquinolines
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1652680