Author/Authors :
Briggs، نويسنده , , Mark S.J and Fossey، نويسنده , , John R. and Richards، نويسنده , , Christopher R. and Scott، نويسنده , , Brian and Whateley، نويسنده , , John، نويسنده ,
Abstract :
Starting from 3-(4-hydroxyphenyl)propanoic acid, formylation ortho to the phenol and condensation with ortho-aminophenol gave a novel functionalised Schiff-base ligand. Formation of the N-hydroxysuccinimidyl ester and non-aqueous complexation with AlEt2Cl gave a novel fluorescent biolabel displaying a Stokes shift of 100 nm. The efficacy of the new system was demonstrated by its attachment to rabbit IgG.