Novel approach to the synthesis of AZT 5′-O-hydrogen phospholipids
Author/Authors :
Xiao، نويسنده , , Qiang and Sun، نويسنده , , Jing and Ju، نويسنده , , Yong and Zhao، نويسنده , , Yu-fen and Cui، نويسنده , , Yu-xin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
3
From page :
5281
To page :
5283
Abstract :
A series of AZT 5′-O-hydrogen phospholipids were synthesized by a tandem transesterification of diphenyl phosphite with AZT and a long-chain alcohol. The method possesses the merits of ease of operation and high yields. It can also be extended to synthesize other biological phospholipids.
Keywords :
phosphorylation , Transesterification , H-phosphonate , AZT , phospholipid
