Title of article
A microbial metabolite inhibitor of CD28–CD80 interactions
Author/Authors
Hegde، نويسنده , , Vinod R and Puar، نويسنده , , Mohindar S and Dai، نويسنده , , Ping and Patel، نويسنده , , Mahesh and Gullo، نويسنده , , Vincent P and Pramanik، نويسنده , , Birendra and Jenh، نويسنده , , Chung-Her، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
5339
To page
5341
Abstract
The organic extract of the fermentation broth of a Streptomycete microorganism was found to contain SCH 212394 (1), a condensed aromatic peptide. The structure was established by extensive NMR spectral data and derivatization. SCH 212394 (1), inhibited CD28–CD80 costimulation with an IC50 of 1.25 μM.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1652851
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