Title of article
Solid-phase synthesis of quinazolin-4(3H)-ones with three-point diversity
Author/Authors
Kesarwani، نويسنده , , A.P. and Srivastava، نويسنده , , G.K. and Rastogi، نويسنده , , S.K and Kundu، نويسنده , , B.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
5579
To page
5581
Abstract
A versatile method for the solid-phase synthesis of differentially substituted quinazolin-4(3H)-ones has been developed using immobilized arylguanidines. The latter were obtained by treating the amino group of polymer-linked anthranilamide with isothiocyanates followed by coupling with secondary amines in the presence of DIC. Finally a cyclative cleavage strategy was applied to give the desired compounds in high yields and purities.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1653001
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