Title of article :
Reaction of aziridinium ions with organometallic reagents: optimization of the key step of ecopipam synthesis
Author/Authors :
Andrews، نويسنده , , David R and Dahanukar، نويسنده , , Vilas H and Eckert، نويسنده , , Jeffrey M and Gala، نويسنده , , Dinesh and Lucas، نويسنده , , Brian S and Schumacher، نويسنده , , Doris P and Zavialov، نويسنده , , Ilia A، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
5
From page :
6121
To page :
6125
Abstract :
Formation, stability and reactivity of aziridinium ions 3 towards organometallic reagents was explored and optimized for the efficient preparation of key drug intermediate 5c.
Keywords :
Grignard reagents , Aziridines , electron affinity , SET mechanism , aziridinium ions
Journal title :
Tetrahedron Letters
Serial Year :
2002
Journal title :
Tetrahedron Letters
Record number :
1653350
Link To Document :
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