Title of article :
Convenient enantioselective synthesis of new 1,4-sulfanylalcohols from γ-lactones
Author/Authors :
Filippi، نويسنده , , Jean-Jacques and Fernandez، نويسنده , , Xavier and Lizzani-Cuvelier، نويسنده , , Louisette and Loiseau، نويسنده , , Andre Michel، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
A synthetic strategy based upon three basic reactions—enzymatic resolution, oxygen–sulfur exchange, reduction—allowed us to carry out an easy and useful synthesis of a series of new 1,4-sulfanylalcohols from aliphatic γ-lactones. Final products have been obtained in good yields with enantiomeric excesses in a 66–91% range.
Keywords :
1 , 4-sulfanylalcohols , enzymatic resolution , Reduction , thionation reaction , ?-Lactones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
