Title of article
Efficient solid-phase synthesis of diverse 1,2,3-benzotriazin-4-ones using tert-butyl nitrite
Author/Authors
Okuzumi، نويسنده , , Tatsuya and Nakanishi، نويسنده , , Eiji and Tsuji، نويسنده , , Takashi and Makino، نويسنده , , Shingo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
5539
To page
5542
Abstract
An efficient synthesis of (−)-chrysolic acid and (+)-isofregenedol has been achieved from zamoranic acid and sclareol. The characteristic tetrahydronaphtalenic system was obtained by use of a cationic rearrangement of bicyclic systems adequately functionalized. The absolute configuration of the natural products was established using Sharpless asymmetric epoxidation.
Keywords
solid-phase synthesis , 1 , 2 , 3-benzotriazin-4-ones , drug , Diazotization
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653589
Link To Document