Title of article
Effect of the alkyl chain length of 1,1′-binaphthyl esters in lipase-catalyzed amidation
Author/Authors
Aoyagi، نويسنده , , Naoto and Kawauchi، نويسنده , , Shinji and Izumi، نويسنده , , Taeko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
5609
To page
5612
Abstract
Lipase-catalyzed amidation of 2-[2-(ethoxycarbonyl)ethyl]-1,1′-binaphthyl [(±)-3] yielded optically active (S)-3 and 2-[2-(2-cyanoethylaminocarbonyl)ethyl]-1,1′-binaphthyl [(R)-6a] with high enantiomeric excess. For these lipase-catalyzed amidations, the optimal alkyl chain length between the binaphthyl ring and the ester group was determined to be an ethylene spacer.
Keywords
Binaphthyl , Suzuki cross-coupling , Lipase , Amidation , Aminolysis
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653607
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