Title of article
Reductive lithiation of alkyl phenyl sulfides in diethyl ether. A ready access to α,α-dialkylbenzyllithiums
Author/Authors
Screttas، نويسنده , , Constantinos G. and Heropoulos، نويسنده , , Georgios A. and Micha-Screttas، نويسنده , , Maria and Steele، نويسنده , , Barry R. and Catsoulacos، نويسنده , , Dimitrios P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
5633
To page
5635
Abstract
Diethyl ether is a convenient solvent for the conversion of benzylic phenyl sulfides to the corresponding organolithiums by an uncatalyzed reductive metalation, while catalysis by naphthalene is required to achieve the same reaction for alkyl phenyl sulfides. The addition of magnesium 2-ethoxyethoxide to solutions of unstable alkyllithiums prepared in this way provides storable reagents.
Keywords
lithiation , Radical anion , magnesium alkoxide , Thioethers , Reduction
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653622
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