Title of article
Templated scaffolds of cis- and trans-tetrahydrofuran γ-amino acids: γ-azido-β-hydroxy-tetrahydrofuran-2-carboxylates from pentono-δ-lactones
Author/Authors
Sanjayan، نويسنده , , Gangadharar J. and Stewart، نويسنده , , Alistair and Hachisu، نويسنده , , Shuji and Gonzalez، نويسنده , , Raquel and Watterson، نويسنده , , Mark P. and Fleet، نويسنده , , George W.J. Fleet، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
5847
To page
5851
Abstract
Short syntheses of enantiomeric templated scaffolds of cis- and trans-tetrahydrofuran γ-amino acids from pentono-δ-lactones derived from arabinose and ribose are reported; an unexpectedly efficient synthesis of a templated tetrahydrofuran β-amino acid by azide displacement of a triflate β to an ester function proceeds with remarkably little elimination. These materials should allow evaluation of such peptidomimetics to induce predisposition towards secondary structures.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653723
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