Title of article
Diastereoselective synthesis of syn-aminoalcohols via contributing CH-π interaction: simple synthesis of (−)-bestatin
Author/Authors
Lee، نويسنده , , Byong Won and Lee، نويسنده , , Jin-Hwan and Jang، نويسنده , , Ki Chang and Kang، نويسنده , , Jae-Eun and Kim، نويسنده , , Jin Hyo and Park، نويسنده , , Ki-Min and Park، نويسنده , , Ki Hun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
5905
To page
5907
Abstract
1H NMR and X-ray crystallography studies revealed that a CH-π and chelation control in aromatic aminoaldehydes (1–6) effects a highly diastereoselective addition to afford optically active syn-aminoalcohols (1a–6a). This methodology was applied to the synthesis of (−)-bestatin.
Keywords
Bestatin , AHPBA , CH-? interaction , syn-aminoalcohol , ?-Hydroxy-?-amino acid
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653750
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