Title of article :
Diastereoselective synthesis of syn-aminoalcohols via contributing CH-π interaction: simple synthesis of (−)-bestatin
Author/Authors :
Lee، نويسنده , , Byong Won and Lee، نويسنده , , Jin-Hwan and Jang، نويسنده , , Ki Chang and Kang، نويسنده , , Jae-Eun and Kim، نويسنده , , Jin Hyo and Park، نويسنده , , Ki-Min and Park، نويسنده , , Ki Hun، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Pages :
3
From page :
5905
To page :
5907
Abstract :
1H NMR and X-ray crystallography studies revealed that a CH-π and chelation control in aromatic aminoaldehydes (1–6) effects a highly diastereoselective addition to afford optically active syn-aminoalcohols (1a–6a). This methodology was applied to the synthesis of (−)-bestatin.
Keywords :
Bestatin , AHPBA , CH-? interaction , syn-aminoalcohol , ?-Hydroxy-?-amino acid
Journal title :
Tetrahedron Letters
Serial Year :
2003
Journal title :
Tetrahedron Letters
Record number :
1653750
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1653750
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