Title of article
One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using boric acid as catalyst
Author/Authors
Tu، نويسنده , , Shujang and Fang، نويسنده , , Fang and Miao، نويسنده , , Chunbao and Jiang، نويسنده , , Hong and Feng، نويسنده , , Youjian and Shi، نويسنده , , Daqing and Wang، نويسنده , , Xiangshan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
6153
To page
6155
Abstract
A simple effective synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives, using boric acid as catalyst, from aromatic aldehydes, 1,3-dicarbonyl compounds and urea in glacial acetic acid is described. Compared with the classical Biginelli reaction conditions, this new method has the advantage of excellent yields (86–97%) and short reaction time (0.5–2 h).
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1653869
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