Efficient enantiomeric resolution via introduction of a fluorous tag as a resolving reagent with β-cyclodextrin columns: model study on fluorinated O-acetylmandelate and ibuprofen amide

Efficient enantiomeric resolution of racemates is performed by introduction of fluorous tags using β-cyclodextrin columns. Selection of appropriate length of tag and mobile phase leads to an efficient resolution of racemates (fluorinated O-acetylmandelate and ibuprofen amide) by those columns.