• Title of article

    A quantitative synthesis of β-carboxylated thiolophosphates via a Michael reaction

  • Author/Authors

    Desforges، نويسنده , , Elisabeth and Grysan، نويسنده , , Alexandre and Oget، نويسنده , , Nicolas and Sindt، نويسنده , , Michèle and Mieloszynski، نويسنده , , Jean-Luc، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    4
  • From page
    6273
  • To page
    6276
  • Abstract
    Reactions of O,O′-dialkylthiophosphoric acids with acrylates provide a direct synthetic route to β-carboxylated thiolophosphates. This Michael addition, without solvent, is quantitative at 90°C in 1 h for the 2/1 thiophosphoric acid/acrylate ratio. Moreover, this excess of thiophosphoric acid can be reused for further reactions.
  • Keywords
    thiophosphoric acid , thiolophosphate , Michael reaction , acrylate
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1653949