Title of article :
A quantitative synthesis of β-carboxylated thiolophosphates via a Michael reaction
Author/Authors :
Desforges، نويسنده , , Elisabeth and Grysan، نويسنده , , Alexandre and Oget، نويسنده , , Nicolas and Sindt، نويسنده , , Michèle and Mieloszynski، نويسنده , , Jean-Luc، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Reactions of O,O′-dialkylthiophosphoric acids with acrylates provide a direct synthetic route to β-carboxylated thiolophosphates. This Michael addition, without solvent, is quantitative at 90°C in 1 h for the 2/1 thiophosphoric acid/acrylate ratio. Moreover, this excess of thiophosphoric acid can be reused for further reactions.
Keywords :
thiophosphoric acid , thiolophosphate , Michael reaction , acrylate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
