Title of article
Regiocontrolled fluorination of 2-hydroxyalkyl dihydropyrans and carbonyl derivatives
Author/Authors
Vu، نويسنده , , Nguyen Quang and Grée، نويسنده , , Danielle and Grée، نويسنده , , René and Brown، نويسنده , , Eric and Dujardin، نويسنده , , Gilles، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
6425
To page
6428
Abstract
Reaction of polysubstituted 2-hydroxyalkyldihydropyrans with DAST led regiospecifically to fluorination at the exocyclic position, except for primary alcohols. Difluorination of carbonylated analogues with deoxo-fluor™ occurred also regioselectively. The unexpected stability and synthetic potential of these new allylic fluorides are discussed.
Keywords
fluorination , DAST , Deoxo-fluor™ , dihydropyran , C-glycoside
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654050
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