Title of article
An efficient synthesis of ortho-N-Boc-arylmethyl ketone derivatives
Author/Authors
Broutin، نويسنده , , Pierre-Emmanuel and Hilty، نويسنده , , Peter and Thomas، نويسنده , , Andrew W، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
6429
To page
6432
Abstract
A new and efficient method for the preparation of ortho-N-Boc-arylmethyl ketone derivatives is reported. The reaction involves the intermediacy of a 4-methylene-3,1-benzoaxin-2-one moiety which smoothly converts to the target compounds under acidic conditions. The ortho-N-Boc-arylmethyl ketone derivatives can be formed in a one-pot reaction or alternatively the 4-methylene-3,1-benzoaxin-2-ones can be isolated and subsequently transformed into the desired products.
Keywords
1-benzoaxin-2-one , polymer supported reagents , 4-methylene-3 , protecting groups , ortho-N-Boc-acetophenone
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654055
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