Author/Authors :
Nagamitsu، نويسنده , , Tohru and Takano، نويسنده , , Daisuke and Shiomi، نويسنده , , Kazuro and Ui، نويسنده , , Hideaki and Yamaguchi، نويسنده , , Yuichi and Masuma، نويسنده , , Rokuro and Harigaya، نويسنده , , Yoshihiro and Kuwajima، نويسنده , , Isao and ?mura، نويسنده , , Satoshi، نويسنده ,
Abstract :
Nafuredin-γ (2) converted from nafuredin (1) under mild basic conditions showed the same inhibitory activity and selectivity against NADH-fumarate reductase as 1. Total synthesis of 2, a proposed active form of 1, has been accomplished by a convergent approach using Stille coupling.